The monastery together with the Church of the Three Hierarchs is considered to be the most beautiful foundation of the ruler Vasile Lupu and, at the same time, an architectonic jewel of the city of Iasi. The religious dwelling was built between 1637 – 1639 and it was consecrated by the Metropolitan Bishop Varlaam on the 6th oh May, 1639.

Carved in stone on the southern facade of the "Three Hierarchs" church, the votive legend reads: "we raised this church in the name of the three saints: Vasile the Great, Gregory the Theologian and John Chrysostome and it was blessed in May, the sixth, 7147 (1639) by the Metropolitan Bishop Varlaam...". All of a sudden, the patrons of the church place the edifice in a world that once belonged to the Holy Fathers of the Church, defenders of the Nicene dogmas, haloed by knowledge and renowned for their ardour. If at that time, during the tormented 4th century AD, the three theologians struggled to save the unity of the church, twelve and a half centuries later the church builders bearing their names succeeded in merging the influence of different worlds into one monument, steeped in the local tradition. The ecclesiastical space thus created counts among the most illustrious of its kind in Romanian art, in the history of the people, of the country and in the Orthodox church. It stands as a landmark of a significant historical time embracing prodigious trends and it is representative for the spirituality of a resourceful community, unique in its artistic achievements.

The builder of this unmatched monument is the pious Prince of Moldavia Vasile Lupu, one of the most distinguished personalities of Romanian History, well-known defender of the Orthodox Church. During the first years of his reign, when the Constantinople Patriarch was in a critical condition - crippled by debts, dominated by intrigues and hit by disorder - Vasile Lupu interfered and tried to put things right. At the same time, later he would pay the debts of the Holy Grave and those of the Athos Mountain monasteries and make many donations as the initiator of some Orthodox Christian religious and charitable works in Poland, Bulgaria and Greece.

Remarkable testimony of the Prince's greatness, the "Three Hierarchs" church stands in the heart of Iaşi, surrounded from the start by Saint Nicholas, Saint Sava, Golia and Barnovski churches, followed successively by other religious and secular monuments, attracted - we could say - by the traditional centre, by the place ennobled by history.

Impressive, it seems to be made to "thunderstrike" the souls of the contemporaries, as it is an answer to the desire for splendour of its builder about who Nicolae Iorga used to say that 'from the second day of his reign he renamed himself Vasile and penetrated the Byzantine dream'. And, indeed, the "Three Hierarchs" church in Iaşi reveals the craving to belong to this astonishing Byzantine world, combining traditional patterns and effects with precious materials and rich ornament.

As also G. Balş reports, the monument observes to a great extent the sixteenth century Moldavian church layout - a triconch plan, influenced by the Galata church, but having an extra turret above the narthex. The vault, observing the ingenious Moldavian vault system, comprises two overlapped rows of four and eight arches that added to the upper pendentives shorten the diameter of the bell turret. Outside, the facade decorative effects remind one of the Dragomirna monastery church (Moldavia 1606 - 1609) and the face divided by a moulding found in Wallachian monasteries.

The ornament is of a wide variety: fascicled archway deep niches like the Oriental patterns, colonnettes like those of Russian churches, Persian vases holding blossomed branches, geometric motifs found also in Georgia and Armenia, the face divided by a rope moulding framed by two Renaissance or Baroque marble strips. All this is arranged in a unity bathed in light. 'Further emphasised by a deep blue stressed by gilt, this decoration fully contributes to the fame that the "Three Hierarchs" church has known ever since it was built. Paul of Alep, archdeacon of Antioch, a fellow-traveller of Patriarch Macarie across the Romanian Principalities, in the sixteenth century, after surveying thoroughly the edifice expressed his entire enthusiasm in the book "Travels" written in Arabian and published in Bucharest in 1900 in a Romanian translation.

The value of mondial singularity is given by the external decoration, an embroidery of rocks, from the bottom up to the eaves’ cornices. On the northern side of the pronaos there are two niches sheltering the bones of the family of the ruler Vasile Lupu, and on the southern side rest the bones of the rulers Dimitrie Cantemir (1710-1711) and Alexandru Ioan Cuza (1859-1866). It’s on this same niche that in 1641 were deposited the relics of Saint Parascheva, having as day of celebration the 14th of October, and in 1889 these were moved in the Metropolitan Cathedral.

By the end of the nineteenth century, the church was restored from the foundation, under the surveillance of the architect André Lecomte de Nouy. The paintings, the catapetasma and the furniture in massive bronze were executed on the expense of King Carol the Ist.

The rededication of the church took place in 1904. The historians record, among others, two important events in the history of the monastery: the interorthodox synod in Iasi, in 1642, when the representatives of the main branches of orthodoxy came here, and the year 1645, when the patriarch Paisie of Jerusalem, former abbot at Manastirea Galata (the Galata Monastery) was anointed.

The printing house established at Trei Ierarhi (Three Hierarchs) is considered to be the first in Moldova. The printing press issued the first book in Romanian “Cartea romaneasca de invatatura” (Romanian Book of Knowledge) (1643), and also other reference books for the Romanian culture. In 1821, it’s from the courtyard of the Monastery Three Hierarchs that was given the signal for the liberation of Greece, through the voice of Alexandru Ipsilanti who presented a Proclamation (28 February 1821) in which he stated the objectives of the Eteria, in it’s fight for the liberation of the Balkan nations. In 1997, in the monastery’s churchyard was unveiled the bust of Mihai Eminescu, who had lived here for a while.

Church’s dedication day is the feast “The Three Holly Hierarchs: Vasile cel Mare (Vasile the Great), Grigore de Nazianz, Ioan Gura de Aur”, on the 30th of January.